Sedative antidepressants and insomnia
نویسندگان
چکیده
منابع مشابه
Sedative antidepressants and insomnia.
OBJECTIVE The present review addresses the relationship between sleep and depression and how serotonergic transmission is implicated in both conditions. METHOD Literature searches were performed in the PubMed and MedLine databases up to March 2010. The terms searched were "insomnia", "depression", "sedative antidepressants" and "serotonin". In order to pinpoint the sedative antidepressants mo...
متن کاملAntidepressants and Insomnia
Mood disorders and insomnia are often comorbid conditions, sharing a complex and bi-directional relationship. Complicating the situation, mood stabilizers can disrupt sleep in a variety of different ways depending on a drug’s mechanism of action, dosage level, and timing of administration. The treatment of comorbid depression and insomnia can be achieved through the use of a sedating antidepres...
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BACKGROUND Sedative hypnotics form an important part of managing insomnia and are recommended for short-term use. It is standard practice for clinicians to inform the patient to use medications only 'when required', but the use of these medications is often chronic. Little is known about the impact of standard labelling/instructions on promoting appropriate medication use for managing insomnia....
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Current pharmacological treatment of insomnia involves the use of sedative-hypnotic benzodiazepine and non-benzodiazepine drugs. Although benzodiazepines improve sleep, their multiple adverse effects hamper their application. Adverse effects include impairment of memory and cognitive functions, next-day hangover and dependence. Non-benzodiazepines are effective for initiating sleep but are not ...
متن کاملTreatment of insomnia in older adults: re-evaluating the benefits and risks of sedative hypnotic agents.
Insomnia and sleep complaints are common among older adults. Although once considered safer than benzodiazepine drugs, recent data on non-benzodiazepine drugs, such as zolpidem (Ambien(®)), have revealed similar negative effects. This issue, as well as others, has been included in the recent updated 2012 American Geriatrics Society Beers Criteria. This article describes the risks and benefits a...
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ژورنال
عنوان ژورنال: Revista Brasileira de Psiquiatria
سال: 2011
ISSN: 1516-4446
DOI: 10.1590/s1516-44462011000100017